Supplements - For Reducing Fat
Supplements No Comments »Walk into any dietary supplement store and you will notice that more products fall into the category of diet or fat loss aids than any other product category. A recent search of an online dietary supplement store indicated that there are close to 400 products that are marketed for fat loss. Fifty-five products contain the dietary supplement, chromium.
Supplements are designed to promote fat loss. The term fat loss will be used rather than weight loss because the latter term does not differentiate between muscle mass and fat mass. Supplements designed to promote fat loss can function on one of a number of different principles. These principles as well as the most commonly used fat loss supplements.
Over the last 20 years, there has been about a 10% increase in the prevalence of overweight individuals. Furthermore, one in five adolescents are considered obese, which is a 45% increase Because of societal pressures, it seems that everyone has used or at least has thought of using a fat loss product at one time or another. This includes adolescents as well as older adults. Just because these supplements are sold in health food and vitamin stores does not guarantee their safety. Some of these supplements may have cross-reactivity with some prescription medications and alcoholic beverages.
Increase in Fat Oxidation
Several factors are involved in the use of lipids as fuel. For muscles to oxidize fatty acids, fat (triacylglycerol) must first be mobilized from the adipose tissue. This is referred to as lipolysis. Once the free fatty acids are lysed and released from adipose tissue, they must be transported by albumin in the blood to the muscle, where uptake occurs via a specific transporter protein called the fatty acid binding protein (FABP) When the free fatty acid (FFA) enters the muscle it is activated, after which the activated fatty acid is transported into the mitochondria where Beeta-oxidation occurs.
Theoretically, an increase in fatty acid oxidation could be achieved at anyone of seven sites. However, the mobilization of free fatty acids from the adipose tissue appears to be the best site because the uptake of FFA by the muscle is dependent on the arterial blood concentration of FFA. The more FFA released by the adipose tissue, the higher the concentration of FFA in the circulation. Therefore, any product that increases lipolysis should increase fatty acid oxidation at the muscle.
Mechanism of Action for Fat Loss Supplements
Supplements marketed to promote fat loss can theoretically function on one of a number of principles, from increasing adipose tissue lipolysis or fat breakdown, to suppressing the appetite or the desire for food to reducing the amount of fat absorbed from food during the digestive process. To better understand how fat loss supplements function, their potential mechanisms of action should first be understood.
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